Reaction-Diffusion Modelling of Interferon Distribution in Secondary Lymphoid Organs

Reaction-Diffusion Modelling of Interferon Distribution in Secondary Lymphoid Organs

This paper proposes a quantitative model of the reaction-diffusion type to examine the distribution of interferon-α (IFNα) in a lymph node (LN). The numerical treatment of the model is based on using an original unstructured mesh generation software Ani3D and nonlinear finite volume method for diffusion equations. The study results in suggestion that due to the variations in hydraulic conductiv...

Prion pathogenesis and secondary lymphoid organs (SLO)

Prion diseases are subacute neurodegenerative diseases that affect humans and a range of domestic and free-ranging animal species. These diseases are characterized by the accumulation of PrP (Sc), an abnormally folded isoform of the cellular prion protein (PrP (C)), in affected tissues. The pathology during prion disease appears to occur almost exclusively within the central nervous system. The...

Cutting Edge: Secondary Lymphoid Organs Are

PRESENCE OF NEUTROPHIL BEARING ANTIGEN IN LYMPHOID ORGANS OF IMMUNE MICE Short title: OVA-FITC neutrophils in secondary lymphoid organs

PRESENCE OF NEUTROPHIL BEARING ANTIGEN IN LYMPHOID ORGANS OF IMMUNE MICE Short title: OVA-FITC neutrophils in secondary lymphoid organs Belkys Angélica Maletto*, Andrea Silvana Rópolo*, Diego Oscar Alignani, Miriam Verónica Liscovsky, Romina Paola Ranocchia, Víctor Gabriel Morón and María Cristina Pistoresi-Palencia. * These authors contributed equally to this work. Departamento de Bioquímica C...

Elucidating the functional anatomy of secondary lymphoid organs.

Functional anatomy offers an attempt to exploit anatomical information as a platform from which to decipher mechanistic details of complex or multistep immunological processes. Immune function depends on structural organization, therefore this approach contributes to a comprehensive understanding of the immune system. Major advances in functional anatomy require progress in both experimental te...